Disease Biomarkers
Biomarkers from blood, urine, and tissue samples for utility in NF clinical trials, with standardized sample collection and methodology protocols.
Leadership
About This Group
The goal of the biomarkers working group are to assess biomarkers collected from blood, urine, and tissue samples for their utility in NF clinical trials. Our group works to (1) define biomarker needs and summarize existing data in NF1, NF2, and Schwannomatosis; (2) outline recommendations for sample collection and biomarker development; and (3) standardize sample collection and methodology protocols where possible to promote comparison between studies by publishing standard operating procedures. Click Here for a Working Group Snapshot
Current group co-leaders: Chetan Bettegowda, MD and Oliver Hanemann, MD, PhD, FRCP · Past group leader: Oliver Hanemann, MD, PhD, FRCP
Defining biomarker needs in NF1, NF2, and Schwannomatosis; outlining recommendations for sample collection; publishing standard operating procedures.
Additional Information
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Working Group Snapshot & Focus Updates
Defining biomarker needs and summarizing existing data in NF1, NF2, and Schwannomatosis. Outlining recommendations for sample collection and biomarker development. Standardizing sample collection and methodology protocols to promote comparison between studies.
Publications & References
Genotype-Phenotype Correlations in Neurofibromatosis and Their Potential Clinical Use
Chetan Bettegowda, Meena Upadhayaya, D. Gareth Evans, AeRang Kim, Dimitrios Mathios, Clemens O. Hanemann. Genotype-Phenotype Correlations in Neurofibromatosis and their Potential Clinical Use. Neurology 2021. Aug 2021; 97 (7 Supplement 1) S91-S98; DOI:10.1212/WNL.0000000000012436.
Current status and recommendations for biomarkers and biobanking in neurofibromatosis
Hanemann CO, Blakeley JO, Nunes FP, et al. Current status and recommendations for biomarkers and biobanking in neurofibromatosis. Neurology 2016 Aug 16;87(7 Suppl 1): S40-8.
Documents & Resources
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Membership is open to all interested parties. Meetings are primarily held by teleconference.
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